Actin regulation refers to the control and modulation of the cytoskeletal protein actin within cells. Actin is a highly abundant protein that plays a critical role in various cellular processes, including cell shape maintenance, cell movement, and intracellular transport. The regulation of actin involves a complex interplay of factors, including actin-binding proteins, signaling pathways, and post-translational modifications. These factors can influence actin polymerization, depolymerization, bundling, and cross-linking, thereby affecting cell motility, cell division, and overall cell structure. Research in the field of actin regulation seeks to understand the intricacies of these regulatory mechanisms and their implications for various cellular functions. This research has important implications for the treatment of diseases such as cancer, where aberrant actin regulation can lead to abnormal cell growth and migration. Additionally, targeting actin regulation has potential therapeutic applications in various other diseases, such as autoimmune disorders and neurodegenerative diseases.